Across TCGA patient cohorts, CES1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,213 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CES1-associated proteins across cancer lineages are MAP1A, TAGLN, and TLN2. Each is linked with CES1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CES1-to-partner and partner-to-CES1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CES1→partner) and Y-score (partner→CES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP1A →	+0.538	+1.531	<.001	<.001	3	7
COAD	TAGLN →	+1.076	+1.452	<.001	<.001	3	6
BRCA	TLN2 →	+0.630	+1.639	<.001	<.001	3	5
OV	TMEM119 →	+0.811	+1.315	<.001	<.001	3	5
OV	TNS2_S102 →	+0.781	+1.199	.001	.001	3	5
BRCA	VCL_S346 →	+0.781	+1.892	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,213 associations by consensus.

Exploration

CES1 survival (RNA) · tumor vs normal (RNA) · all CES1 data types