Across TCGA patient cohorts, CES1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,464 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CES1-associated genes across cancer lineages are DCN, CCN2, and SERPINF1. Each is linked with CES1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CES1-to-partner and partner-to-CES1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CES1→partner) and Y-score (partner→CES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DCN →	+2.028	+1.246	<.001	<.001	3	8
OV	CCN2 →	+1.833	+1.197	<.001	<.001	3	7
OV	SERPINF1 →	+1.741	+0.977	<.001	<.001	3	7
BRCA	COLEC12 →	+0.916	+0.762	<.001	<.001	3	7
OV	SPSB1 →	+0.794	+0.913	<.001	<.001	3	7
LSCC	CES1P1 →	+1.540	+1.457	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,464 associations by consensus.

Exploration

CES1 survival (RNA) · tumor vs normal (RNA) · all CES1 data types