CERT1

Across TCGA cell cohorts, CERT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,855 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CERT1-associated GO terms across cancer lineages are Cytosolic transport, Endosomal transport, and Glycerophospholipid metabolic process. Each is linked with CERT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CERT1-to-partner and partner-to-CERT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by CERT1-low versus CERT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CERT1→partner) and Y-score (partner→CERT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.087	+0.967	<.001	.001	3	14
SOFT_TISSUE	Endosomal transport →	+0.050	+0.632	<.001	<.001	3	13
SKIN	Glycerophospholipid metabolic process →	+0.045	+1.165	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.052	+0.738	.005	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Dephosphorylation →	+0.041	+0.770	<.001	.002	3	12
LARGE_INTESTINE	Process utilizing autophagic mechanism →	+0.055	+0.857	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,855 associations by consensus.

Cytosolic transport by CERT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →