CERS5

Across TCGA patient cohorts, CERS5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,096 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CERS5-associated genes across cancer lineages are TWIST2, RDXP3, and SEC63. Each is linked with CERS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CERS5-to-partner and partner-to-CERS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERS5 versus TWIST2 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS5→partner) and Y-score (partner→CERS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TWIST2 →	+0.923	+0.400	<.001	.002	3	2
HNSC	RDXP3 →	+0.453	+0.273	.007	.007	3	2
COAD	SEC63 →	+0.578	+0.301	.004	.007	3	2
COAD	DDTL →	+1.097	+0.499	.003	.001	3	2
BRCA	RASIP1 →	-0.675	-0.642	<.001	.001	3	2
LSCC	SLC22A3 →	-0.882	-0.416	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,096 associations by consensus.

CERS5 vs TWIST2 — OV

Explore this scatter interactively →