CERS2

Across TCGA patient cohorts, CERS2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,335 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CERS2-associated genes across cancer lineages are HAX1, ADIPOR1, and PSMD4. Each is linked with CERS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CERS2-to-partner and partner-to-CERS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERS2 versus HAX1 in COAD, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS2→partner) and Y-score (partner→CERS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HAX1 →	+0.588	+0.412	<.001	<.001	3	5
BRCA	ADIPOR1 →	+0.484	+0.741	<.001	<.001	3	5
LSCC	PSMD4 →	+0.469	+0.274	<.001	<.001	3	5
LUAD	MARVELD2 →	+0.752	+0.374	<.001	<.001	3	5
UCEC	MLKL →	-0.479	-0.294	.003	.006	3	5
BRCA	SLC50A1 →	+0.514	+0.594	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,335 associations by consensus.

CERS2 vs HAX1 — COAD

Explore this scatter interactively →