Across TCGA cell cohorts, CERS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,374 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CERS1-associated GO terms across cancer lineages are Positive regulation of sodium ion transport, Positive regulation of monoatomic ion transmembrane transport, and Intracellular sodium ion homeostasis. Each is linked with CERS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CERS1-to-partner and partner-to-CERS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS1→partner) and Y-score (partner→CERS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of sodium ion transport →	-0.185	-1.459	<.001	.005	3	14
BREAST	Positive regulation of monoatomic ion transmembrane transport →	-0.099	-1.343	<.001	.002	3	12
BREAST	Intracellular sodium ion homeostasis →	-0.254	-1.658	<.001	<.001	3	12
BONE	Regulation of potassium ion import →	-0.208	-1.998	<.001	<.001	3	11
OVARY	Positive regulation of monoatomic ion transport →	-0.116	-2.113	<.001	<.001	3	11
OESOPHAGUS	Protein-DNA complex organization →	+0.086	+1.948	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,374 associations by consensus.

Exploration

CERS1 survival (RNA) · tumor vs normal (RNA) · all CERS1 data types