Across TCGA patient cohorts, CERKL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,481 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CERKL-associated proteins across cancer lineages are TPPP3, WDR19, and AGR3. Each is linked with CERKL in more than 5 cancer types. Because this analysis shows association rather than direction, both CERKL-to-partner and partner-to-CERKL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CERKL→partner) and Y-score (partner→CERKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TPPP3 →	+1.237	+0.886	<.001	<.001	3	6
UCEC	WDR19 →	+0.422	+0.937	<.001	.001	3	5
UCEC	AGR3 →	+1.282	+1.036	<.001	<.001	3	5
BRCA	DDAH1 →	+0.662	+0.571	<.001	<.001	3	5
UCEC	DNALI1 →	+0.768	+0.871	<.001	.004	3	5
BRCA	IFT140 →	+0.402	+0.640	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,481 associations by consensus.

Exploration

CERKL survival (RNA) · tumor vs normal (RNA) · all CERKL data types