CERCAM

Across TCGA patient cohorts, CERCAM RNA expression is significantly associated with the protein abundance of many other proteins, with 20,566 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CERCAM-associated proteins across cancer lineages are THBS1, THBS2, and TIMP2. Each is linked with CERCAM in more than 7 cancer types. Because this analysis shows association rather than direction, both CERCAM-to-partner and partner-to-CERCAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERCAM versus THBS1 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CERCAM→partner) and Y-score (partner→CERCAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THBS1 →	+0.933	+0.866	<.001	<.001	3	8
OV	THBS2 →	+1.583	+1.124	<.001	<.001	3	8
OV	TIMP2 →	+0.726	+1.206	<.001	<.001	3	8
OV	VCAN →	+1.436	+1.206	<.001	<.001	3	8
LSCC	P3H1 →	+0.576	+0.820	<.001	<.001	3	8
OV	P3H3 →	+0.823	+1.334	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,566 associations by consensus.

CERCAM vs THBS1 — OV

Explore this scatter interactively →