CERCAM

Across TCGA patient cohorts, CERCAM protein abundance is significantly associated with the RNA expression of many other genes, with 9,862 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CERCAM-associated genes across cancer lineages are ACTA2, COL1A1, and COL12A1. Each is linked with CERCAM in more than 6 cancer types. Because this analysis shows association rather than direction, both CERCAM-to-partner and partner-to-CERCAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERCAM versus ACTA2 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERCAM→partner) and Y-score (partner→CERCAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ACTA2 →	+2.105	+0.614	<.001	<.001	3	7
OV	COL1A1 →	+2.309	+0.441	<.001	<.001	3	7
BRCA	COL12A1 →	+1.924	+0.601	<.001	<.001	3	7
OV	COL5A1 →	+1.939	+0.391	<.001	<.001	3	7
OV	POSTN →	+3.341	+0.447	<.001	<.001	3	7
OV	LUM →	+2.332	+0.393	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,862 associations by consensus.

CERCAM vs ACTA2 — OV

Explore this scatter interactively →