CEPT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CEPT1 mutation is significantly associated with the RNA expression of many other genes, with 1,586 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEPT1-associated genes across cancer lineages are NMNAT1P4, RAC1P7, and OR7E53P. Each is linked with CEPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEPT1-to-partner and partner-to-CEPT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMNAT1P4 grouped by CEPT1-low versus CEPT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEPT1→partner) and Y-score (partner→CEPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNMNAT1P4 →+0.049+5.634<.001.00132
SKCMRAC1P7 →+0.106+5.039<.001.00331
SKCMOR7E53P →+0.087+4.877<.001<.00131
SKCMRN7SL849P →+0.344+4.551<.001.00131
BLCARN7SL357P →+0.229+5.251<.001.00631
UCECIMMP1L →+0.390+2.254.006.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,586 associations by consensus.

NMNAT1P4 by CEPT1 expression — SKCM

Box plot of NMNAT1P4 in CEPT1-low vs CEPT1-high samples in SKCM.

Explore this box plot interactively →

Exploration