CEPT1

Across TCGA cell cohorts, CEPT1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEPT1-associated genes across cancer lineages are GFRA4, PPDPFL, and ARGFX. Each is linked with CEPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEPT1-to-partner and partner-to-CEPT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by CEPT1-low versus CEPT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEPT1→partner) and Y-score (partner→CEPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GFRA4 →	+0.019	+3.345	.001	.007	3	1
LARGE_INTESTINE	PPDPFL →	+0.040	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ARGFX →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ZNF679 →	+0.027	+3.347	<.001	.005	3	1
LARGE_INTESTINE	SCYGR2 →	+0.043	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	KRTAP17-1 →	+0.021	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GFRA4 by CEPT1 expression — LARGE_INTESTINE

Explore this box plot interactively →