CEP97

Across TCGA pan-cancer cohorts, CEP97 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CEP97 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CEP97 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CEP97 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

PDAC, HNSC, and GBM are the cancer types where CEP97 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.654	0.986	<.001	83	view →
HNSC	DFS	Quartile	II,III,IV	0.937	0.724	.021	10	view →
GBM	DFS	Tertile	All	0.858	0.590	.006	8	view →
CCRCC	DFS	Median	II,III,IV	0.797	0.930	.023	4	view →
LSCC	DFS	Median	All	0.795	0.621	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CEP97–PDAC (OS)

Open the PDAC breakdown →