CEP95

Across TCGA pan-cancer cohorts, CEP95 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CEP95 data layer compared with 4 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CEP95 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CEP95 expression acts as an unfavorable survival marker, although some lineages such as READ and BRCA show a favorable association.

ACC, KIRC, and LIHC are the cancer types where CEP95 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.234	0.659	<.001	134	view →
KIRC	DFS	Quartile	II,III,IV	0.366	0.632	.001	85	view →
LIHC	DFS	Median	All	0.464	0.615	<.001	72	view →
KICH	OS	Median	All	0.633	1.000	.001	67	view →
READ	OS	Median	II,III,IV	0.750	0.466	.002	48	view →
BRCA	OS	Quartile	III,IV	0.970	0.837	.003	47	view →
UCS	OS	Tertile	II,III,IV	0.789	0.365	.007	40	view →
CESC	DFS	Tertile	III,IV	0.564	0.921	.002	34	view →
LGG	DFS	Median	All	0.299	0.456	<.001	31	view →
PRAD	DFS	Quartile	All	0.712	0.946	<.001	26	view →
THYM	OS	Tertile	All	1.000	0.684	.002	20	view →
BLCA	DFS	Tertile	IV	0.352	0.191	.011	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CEP95–ACC (DFS)

Open the ACC breakdown →