CEP85

Across TCGA patient cohorts, CEP85 mutation is significantly associated with the RNA expression of many other genes, with 3,347 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP85-associated genes across cancer lineages are BNIP3P41, ADAM33, and CACNA1C. Each is linked with CEP85 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP85-to-partner and partner-to-CEP85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by CEP85-low versus CEP85-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP85→partner) and Y-score (partner→CEP85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BNIP3P41 →	+0.008	+3.723	<.001	.008	3	3
UCEC	ADAM33 →	-0.761	-1.927	.003	.001	3	2
UCEC	CACNA1C →	-0.397	-3.766	.003	<.001	3	2
UCEC	UBAP1 →	+0.463	+2.263	<.001	<.001	3	2
UCEC	NDUFB6 →	+0.405	+2.425	.002	.001	3	2
UCEC	STOML2 →	+0.417	+2.643	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,347 associations by consensus.

BNIP3P41 by CEP85 expression — UCEC

Explore this box plot interactively →