CEP85

Across TCGA cell cohorts, CEP85 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CEP85-associated genes across cancer lineages are SLC36A3, PRAMEF9, and H2BC1. Each is linked with CEP85 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP85-to-partner and partner-to-CEP85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC36A3 grouped by CEP85-low versus CEP85-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP85→partner) and Y-score (partner→CEP85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SLC36A3 →	+0.018	+3.866	.002	.006	3	2
URINARY_TRACT	PRAMEF9 →	+0.013	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	H2BC1 →	+0.436	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR5T2 →	+0.007	+4.078	<.001	.009	3	1
CNS	OR4D2 →	+0.015	+5.357	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SLC36A3 by CEP85 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →