CEP83

Across TCGA patient cohorts, CEP83 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP83-associated genes across cancer lineages are FoxM1, 14-3-3_beta, and EGFR_pY1068. Each is linked with CEP83 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP83-to-partner and partner-to-CEP83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by CEP83-low versus CEP83-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP83→partner) and Y-score (partner→CEP83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.186	+1.736	.038	.007	3	2
UCEC	14-3-3_beta →	-0.098	-2.558	.004	.010	3	1
UCEC	EGFR_pY1068 →	-0.302	-2.070	<.001	.001	3	1
UCEC	A-Raf_pS299 →	-0.135	-2.222	.001	.010	3	1
UCEC	GATA6 →	-0.117	-1.355	.032	.036	3	1
UCEC	ACC1 →	+0.345	+2.321	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

FoxM1 by CEP83 expression — UCEC

Explore this box plot interactively →