CEP78

Across TCGA cell cohorts, CEP78 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CEP78-associated genes across cancer lineages are IL22, PCDH11Y, and GABRG3. Each is linked with CEP78 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP78-to-partner and partner-to-CEP78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL22 grouped by CEP78-low versus CEP78-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP78→partner) and Y-score (partner→CEP78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IL22 →	+0.023	+5.087	<.001	.004	3	1
URINARY_TRACT	PCDH11Y →	+0.016	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	GABRG3 →	+0.419	+3.727	<.001	.005	3	1
LUNG_NSCLC_LUAD	SHISA6 →	+0.360	+3.628	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR2C3 →	+0.457	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	ZNF99 →	+0.232	+4.299	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

IL22 by CEP78 expression — URINARY_TRACT

Explore this box plot interactively →