CEP72

Across TCGA patient cohorts, CEP72 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP72-associated genes across cancer lineages are Rad50, TFRC, and 14-3-3_beta. Each is linked with CEP72 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP72-to-partner and partner-to-CEP72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by CEP72-low versus CEP72-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP72→partner) and Y-score (partner→CEP72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.218	-1.847	.014	.008	3	2
UCEC	TFRC →	+0.394	+1.847	.043	.008	3	2
UCEC	14-3-3_beta →	-0.080	-1.673	.031	.040	3	1
UCEC	GAPDH →	+0.403	+2.321	.041	.033	3	1
UCEC	IGFBP2 →	-0.644	-1.874	.006	.049	3	1
UCEC	JNK2 →	+0.198	+1.901	.006	.028	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Rad50 by CEP72 expression — UCEC

Explore this box plot interactively →