CEP68

Across TCGA pan-cancer cohorts, CEP68 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CEP68 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CEP68 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CEP68 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where CEP68 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	0.286	1.000	.013	20	view →
CCRCC	DFS	Median	All	0.898	0.730	.022	10	view →
HNSC	OS	Median	All	0.449	1.000	.023	7	view →
GBM	OS	Median	All	0.474	0.301	.039	4	view →
PDAC	DFS	Median	II,III,IV	0.517	0.321	.016	4	view →
LUAD	DFS	Quartile	II,III,IV	0.644	0.975	.011	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CEP68–UCEC (OS)

Open the UCEC breakdown →