CEP63

Across TCGA pan-cancer cohorts, CEP63 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CEP63 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CEP63 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CEP63 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and HNSC are the cancer types where CEP63 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	1.000	0.230	.002	24	view →
LSCC	OS	Tertile	II,III,IV	0.955	0.652	.002	22	view →
HNSC	OS	Median	All	0.520	1.000	.040	6	view →
CCRCC	DFS	Tertile	All	0.633	0.899	.029	2	view →
LUAD	DFS	Median	All	0.687	0.939	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CEP63–UCEC (DFS)

Open the UCEC breakdown →