CEP63

Across TCGA cell cohorts, CEP63 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,511 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEP63-associated GO terms across cancer lineages are Negative regulation of protein K63-linked ubiquitination, Negative regulation of protein polyubiquitination, and Regulation of protein K63-linked ubiquitination. Each is linked with CEP63 in more than 13 cancer types. Because this analysis shows association rather than direction, both CEP63-to-partner and partner-to-CEP63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein K63-linked ubiquitination grouped by CEP63-low versus CEP63-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP63→partner) and Y-score (partner→CEP63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of protein K63-linked ubiquitination →	+0.167	+0.666	.001	.003	3	14
URINARY_TRACT	Negative regulation of protein polyubiquitination →	+0.169	+0.668	<.001	.004	3	14
LUNG_SCLC	Regulation of protein K63-linked ubiquitination →	+0.174	+0.710	<.001	<.001	3	13
LUNG_SCLC	Regulation of protein polyubiquitination →	+0.119	+0.730	<.001	<.001	3	12
OVARY	Protein localization to microtubule cytoskeleton →	+0.071	+0.746	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.064	+0.609	.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,511 associations by consensus.

Negative regulation of protein K63-linked ubiquitination by CEP63 expression — BREAST

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