CEP63

Across TCGA cell cohorts, CEP63 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CEP63-associated genes across cancer lineages are ALPI, SLC38A8, and OR10K1. Each is linked with CEP63 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP63-to-partner and partner-to-CEP63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALPI grouped by CEP63-low versus CEP63-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP63→partner) and Y-score (partner→CEP63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ALPI →	+0.295	+3.192	<.001	.008	3	2
BLOOD_Lymphoma	SLC38A8 →	+0.072	+3.606	<.001	.002	3	2
BLOOD_Lymphoma	OR10K1 →	+0.004	+3.867	.008	.002	3	2
URINARY_TRACT	FABP9 →	+0.056	+5.087	<.001	.004	3	1
LUNG_SCLC	LYZL2 →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	GRIFIN →	+0.117	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

ALPI by CEP63 expression — BLOOD_Lymphoma

Explore this box plot interactively →