Across TCGA pan-cancer cohorts, CEP57L1P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CEP57L1P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CEP57L1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types CEP57L1P1 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

KIRP, HNSC, and UCEC are the cancer types where CEP57L1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP57L1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	−0.078	<.001	6	view →
HNSC	Male	II,III,IV	+0.057	.002	6	view →
UCEC	All	III,IV	+0.161	.025	4	view →
THCA	All	All	−0.032	.011	2	view →
BLCA	Male	III,IV	+0.079	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CEP57L1P1 RNA expression & survival · all CEP57L1P1 data types