CEP57L1

Across TCGA patient cohorts, CEP57L1 protein abundance is significantly associated with the RNA expression of many other genes, with 273 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CEP57L1-associated genes across cancer lineages are STS, ZC3H12B, and HHATL. Each is linked with CEP57L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP57L1-to-partner and partner-to-CEP57L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP57L1 versus STS in BRCA, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP57L1→partner) and Y-score (partner→CEP57L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STS →	-1.528	-0.915	.002	.003	3	1
BRCA	ZC3H12B →	+0.484	+0.749	.006	.001	3	1
BRCA	HHATL →	-0.178	-0.776	.003	.004	3	1
BRCA	TOX3 →	-2.364	-0.781	.002	.006	3	1
BRCA	RIPK2 →	+1.366	+0.750	.001	.009	3	1
BRCA	AMH →	-2.148	-0.692	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 273 associations by consensus.

CEP57L1 vs STS — BRCA

Explore this scatter interactively →