CEP57

Across TCGA patient cohorts, CEP57 protein abundance is significantly associated with the RNA expression of many other genes, with 8,526 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CEP57-associated genes across cancer lineages are LRRN4CL, ADAMTS7P4, and RASSF1. Each is linked with CEP57 in more than 4 cancer types. Because this analysis shows association rather than direction, both CEP57-to-partner and partner-to-CEP57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP57 versus LRRN4CL in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP57→partner) and Y-score (partner→CEP57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRN4CL →	+1.100	+0.342	<.001	<.001	3	5
LSCC	ADAMTS7P4 →	+0.286	+0.224	<.001	.001	3	5
OV	RASSF1 →	+1.269	+0.665	.006	.004	3	4
UCEC	NDRG1 →	-1.224	-0.300	.002	<.001	3	4
UCEC	CPED1 →	+1.164	+0.348	<.001	<.001	3	4
CCRCC	TEK →	+1.125	+0.217	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,526 associations by consensus.

CEP57 vs LRRN4CL — UCEC

Explore this scatter interactively →