CEP44

Across TCGA pan-cancer cohorts, CEP44 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CEP44’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where CEP44 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CEP44 is over-expressed in tumor, although a few such as LSCC and COAD show the opposite, repressed pattern.

LSCC, COAD, and LUAD are the cancer types where CEP44 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP44 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Female	All	−0.297	<.001	8	view →
COAD	All	All	−0.240	.005	5	view →
LUAD	All	III,IV	−0.153	.003	4	view →
OV	All	All	−0.436	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CEP44–LSCC

Open the LSCC breakdown →