Across TCGA pan-cancer cohorts, CEP43 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CEP43 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CEP43 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CEP43 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where CEP43 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	1.000	0.476	.004	32	view →
LUAD	DFS	Median	III,IV	0.977	0.504	.005	19	view →
UCEC	DFS	Median	III,IV	0.900	0.499	.025	4	view →
GBM	OS	Quartile	All	0.429	0.644	.045	2	view →
LSCC	OS	Median	All	0.832	0.938	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CEP43 tumor-vs-normal RNA expression · all CEP43 data types