Across TCGA patient cohorts, CEP43 mutation is significantly associated with the RNA expression of many other genes, with 542 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP43-associated genes across cancer lineages are RPL12P5, TRDJ2, and IGHD6-13. Each is linked with CEP43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP43-to-partner and partner-to-CEP43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP43→partner) and Y-score (partner→CEP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL12P5 →	+0.122	+4.282	<.001	.009	3	2
UCEC	TRDJ2 →	+0.676	+2.141	.007	.004	3	2
UCEC	IGHD6-13 →	+0.590	+2.622	<.001	.007	3	2
UCEC	LINC02647 →	+0.069	+3.335	.003	.004	3	2
UCEC	TCP11X3P →	+0.323	+2.087	<.001	.005	3	2
UCEC	IGLJCOR18 →	+0.447	+2.422	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 542 associations by consensus.

Exploration

CEP43 survival (RNA) · tumor vs normal (RNA) · all CEP43 data types