Across TCGA patient cohorts, CEP43 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP43-associated genes across cancer lineages are eEF2, FOXO3a_pS318_S321, and GAPDH. Each is linked with CEP43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP43-to-partner and partner-to-CEP43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP43→partner) and Y-score (partner→CEP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.533	+3.169	<.001	.018	3	1
UCEC	FOXO3a_pS318_S321 →	-0.173	-3.449	.002	.005	3	1
UCEC	GAPDH →	+0.587	+3.000	.015	.036	3	1
UCEC	INPP4B →	-0.294	-1.986	.044	.032	3	1
UCEC	JNK_pT183_Y185 →	-0.193	-2.687	.011	.006	3	1
UCEC	JNK2 →	+0.327	+3.469	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

CEP43 survival (RNA) · tumor vs normal (RNA) · all CEP43 data types