CEP41

Across TCGA pan-cancer cohorts, CEP41 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CEP41 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CEP41 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CEP41 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

LSCC, PDAC, and CCRCC are the cancer types where CEP41 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.916	1.000	.004	35	view →
PDAC	DFS	Median	IV	0.766	0.234	.026	6	view →
CCRCC	OS	Quartile	All	0.657	1.000	.035	4	view →
LUAD	DFS	Quartile	All	0.586	0.963	.029	2	view →
UCEC	OS	Quartile	All	0.899	1.000	.033	2	view →
GBM	OS	Tertile	All	0.930	0.785	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CEP41–LSCC (OS)

Open the LSCC breakdown →