CEP350

Across TCGA patient cohorts, CEP350 mutation is significantly associated with the RNA expression of many other genes, with 6,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP350-associated genes across cancer lineages are CLEC14A, MIR3145, and TSFM. Each is linked with CEP350 in more than 4 cancer types. Because this analysis shows association rather than direction, both CEP350-to-partner and partner-to-CEP350 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC14A grouped by CEP350-low versus CEP350-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP350→partner) and Y-score (partner→CEP350) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLEC14A →	-0.291	-1.804	.007	.001	3	5
BRCA	MIR3145 →	+0.350	+1.945	.006	.007	3	4
UCEC	TSFM →	+0.307	+1.265	<.001	<.001	3	4
UCEC	DAD1 →	+0.384	+1.573	<.001	<.001	3	4
UCEC	PES1 →	+0.486	+1.754	<.001	<.001	3	4
UCEC	SNU13 →	+0.291	+1.407	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,403 associations by consensus.

CLEC14A by CEP350 expression — UCEC

Explore this box plot interactively →