CEP295NL

Across TCGA patient cohorts, CEP295NL mutation is significantly associated with the RNA expression of many other genes, with 2,218 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP295NL-associated genes across cancer lineages are KPNA2P1, PSMA6P4, and OXSM. Each is linked with CEP295NL in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP295NL-to-partner and partner-to-CEP295NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KPNA2P1 grouped by CEP295NL-low versus CEP295NL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP295NL→partner) and Y-score (partner→CEP295NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KPNA2P1 →	+0.183	+3.716	<.001	.003	3	3
LIHC	PSMA6P4 →	+0.061	+4.274	.002	.008	3	2
UCEC	OXSM →	+0.353	+3.642	.001	.001	3	2
UCEC	TMEM263 →	+0.498	+3.708	.005	<.001	3	2
UCEC	SKA1 →	+0.799	+2.747	<.001	<.001	3	2
UCEC	OXER1 →	-0.527	-1.847	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,218 associations by consensus.

KPNA2P1 by CEP295NL expression — COAD

Explore this box plot interactively →