CEP295

Across TCGA patient cohorts, CEP295 protein abundance is significantly associated with the RNA expression of many other genes, with 795 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CEP295-associated genes across cancer lineages are RNU2-7P, SIGLEC1, and HSPE1P21. Each is linked with CEP295 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP295-to-partner and partner-to-CEP295 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP295 versus RNU2-7P in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP295→partner) and Y-score (partner→CEP295) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNU2-7P →	+1.020	+0.596	<.001	.002	3	2
BRCA	SIGLEC1 →	-1.188	-0.921	.002	.005	3	2
UCEC	HSPE1P21 →	-1.750	-0.685	.003	.004	3	1
UCEC	NECAP1 →	-0.349	-0.602	.001	.001	3	1
LUAD	TSNAXIP1 →	-0.502	-0.455	.002	.003	3	1
BRCA	ARRDC2 →	-1.017	-1.122	.001	.001	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 795 associations by consensus.

CEP295 vs RNU2-7P — LSCC

Explore this scatter interactively →