CEP20

Across TCGA patient cohorts, CEP20 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP20-associated genes across cancer lineages are SELENOKP2, GRPEL2P2, and MTND1P33. Each is linked with CEP20 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP20-to-partner and partner-to-CEP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SELENOKP2 grouped by CEP20-low versus CEP20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP20→partner) and Y-score (partner→CEP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SELENOKP2 →	+0.406	+3.999	.002	.002	3	2
UCEC	GRPEL2P2 →	+0.137	+3.813	<.001	<.001	3	2
SKCM	MTND1P33 →	+0.044	+5.039	<.001	.003	3	2
SKCM	RPS28P8 →	+0.254	+5.039	<.001	.003	3	2
UCEC	FXNP2 →	+0.264	+3.039	.002	.005	3	1
UCEC	HMX3 →	+0.757	+3.122	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

SELENOKP2 by CEP20 expression — UCEC

Explore this box plot interactively →