CEP20

Across TCGA cell cohorts, CEP20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,101 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CEP20-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cell PML body, Regulation of cell cycle checkpoint, and Circadian sleep/wake cycle. Each is linked with CEP20 in more than 11 cancer types. Because this analysis shows association rather than direction, both CEP20-to-partner and partner-to-CEP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cell PML body grouped by CEP20-low versus CEP20-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP20→partner) and Y-score (partner→CEP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Symbiont-mediated disruption of host cell PML body →	+0.094	+0.842	.003	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle checkpoint →	+0.090	+0.869	.003	.007	3	11
BREAST	Circadian sleep/wake cycle →	+0.143	+0.749	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.081	+0.936	.003	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.100	+1.180	<.001	<.001	3	9
BREAST	Telomere maintenance via telomerase →	+0.089	+0.835	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,101 associations by consensus.

Symbiont-mediated disruption of host cell PML body by CEP20 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →