CEP192

Across TCGA patient cohorts, CEP192 mutation is significantly associated with the total protein of many other genes, with 97 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CEP192-associated genes across cancer lineages are Cyclin-B1, ASNS, and eIF4E. Each is linked with CEP192 in more than 4 cancer types. Because this analysis shows association rather than direction, both CEP192-to-partner and partner-to-CEP192 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by CEP192-low versus CEP192-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP192→partner) and Y-score (partner→CEP192) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cyclin-B1 →	+0.490	+3.459	.019	.005	3	5
COAD	ASNS →	+0.554	+2.230	<.001	.006	3	4
COAD	eIF4E →	+0.274	+3.472	<.001	.002	3	3
STAD	HSP70 →	-0.575	-3.459	.011	.005	3	3
COAD	PCNA →	+0.306	+2.915	.001	<.001	2	4
COAD	Caspase-7-cleavedD198 →	+2.163	+2.915	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Cyclin-B1 by CEP192 expression — STAD

Explore this box plot interactively →