CEP170P1

Across TCGA patient cohorts, CEP170P1 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP170P1-associated genes across cancer lineages are Annexin-1, ATM, and 14-3-3_beta. Each is linked with CEP170P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP170P1-to-partner and partner-to-CEP170P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by CEP170P1-low versus CEP170P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP170P1→partner) and Y-score (partner→CEP170P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.580	+3.341	.005	.005	3	2
UCEC	ATM →	-0.494	-2.000	.005	.010	3	2
UCEC	14-3-3_beta →	-0.132	-2.886	<.001	.001	3	1
UCEC	EGFR_pY1068 →	-0.240	-2.459	.014	.019	3	1
UCEC	A-Raf_pS299 →	-0.105	-2.321	.025	.034	3	1
UCEC	ERK2 →	+0.204	+2.700	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Annexin-1 by CEP170P1 expression — UCEC

Explore this box plot interactively →