CEP170B

Across TCGA patient cohorts, CEP170B mutation is significantly associated with the RNA expression of many other genes, with 3,635 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP170B-associated genes across cancer lineages are YBX1P2, PPP1R8, and CDCA8. Each is linked with CEP170B in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP170B-to-partner and partner-to-CEP170B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YBX1P2 grouped by CEP170B-low versus CEP170B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP170B→partner) and Y-score (partner→CEP170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YBX1P2 →	+0.459	+3.828	<.001	<.001	3	3
UCEC	PPP1R8 →	+0.371	+2.928	.001	<.001	3	3
UCEC	CDCA8 →	+0.567	+4.016	.004	<.001	3	3
UCEC	AGBL2 →	-0.587	-3.169	.001	<.001	3	3
UCEC	CCDC163 →	+0.386	+2.185	.001	.001	3	2
LUAD	RPL23AP24 →	+0.079	+4.418	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

YBX1P2 by CEP170B expression — UCEC

Explore this box plot interactively →