CEP170B

Across TCGA cell cohorts, CEP170B mutation is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP170B-associated genes across cancer lineages are A3GALT2, OR5B21, and OR6F1. Each is linked with CEP170B in more than 3 cancer types. Because this analysis shows association rather than direction, both CEP170B-to-partner and partner-to-CEP170B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A3GALT2 grouped by CEP170B-low versus CEP170B-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP170B→partner) and Y-score (partner→CEP170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	A3GALT2 →	+0.039	+4.129	.004	.002	3	4
LUNG_SCLC	OR5B21 →	+0.049	+4.269	<.001	.005	3	2
BLOOD_Lymphoma	OR6F1 →	+0.111	+4.058	<.001	.009	3	2
SKIN	MBOAT2 →	+0.686	+2.451	.008	.009	3	2
LARGE_INTESTINE	PIGH →	+0.448	+3.169	.004	.009	3	2
LARGE_INTESTINE	SEMA3G →	+0.688	+2.043	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

A3GALT2 by CEP170B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →