CEP170

Across TCGA cell cohorts, CEP170 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,129 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP170-associated GO terms across cancer lineages are Regulation of cytokinesis, Protein localization to nucleus, and Microtubule polymerization. Each is linked with CEP170 in more than 15 cancer types. Because this analysis shows association rather than direction, both CEP170-to-partner and partner-to-CEP170 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytokinesis grouped by CEP170-low versus CEP170-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP170→partner) and Y-score (partner→CEP170) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of cytokinesis →	+0.115	+2.129	<.001	<.001	3	16
BLOOD_Lymphoma	Protein localization to nucleus →	+0.064	+1.279	<.001	<.001	3	15
LARGE_INTESTINE	Microtubule polymerization →	+0.104	+1.360	.001	<.001	3	14
LIVER	Regulation of cilium assembly →	+0.070	+1.144	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.103	+1.339	<.001	<.001	3	14
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.119	+1.239	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,129 associations by consensus.

Regulation of cytokinesis by CEP170 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →