CEP164

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CEP164 mutation is significantly associated with the RNA expression of many other genes, with 6,043 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP164-associated genes across cancer lineages are PIMREG, ZNF736P7Y, and NUSAP1. Each is linked with CEP164 in more than 3 cancer types. Because this analysis shows association rather than direction, both CEP164-to-partner and partner-to-CEP164 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIMREG grouped by CEP164-low versus CEP164-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP164→partner) and Y-score (partner→CEP164) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPIMREG →+0.776+2.301<.001<.00134
LUSCZNF736P7Y →+0.084+3.377<.001.00434
UCECNUSAP1 →+0.817+2.544<.001<.00134
UCECMCM10 →+0.689+1.830<.001<.00134
UCECCOPS3 →+0.574+2.044<.001<.00134
COADF10 →-1.158-3.459.005.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,043 associations by consensus.

PIMREG by CEP164 expression — UCEC

Box plot of PIMREG in CEP164-low vs CEP164-high samples in UCEC.

Explore this box plot interactively →

Exploration