CEP164

Across TCGA patient cohorts, CEP164 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP164-associated genes across cancer lineages are PCNA, ASNS, and ATM. Each is linked with CEP164 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP164-to-partner and partner-to-CEP164 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by CEP164-low versus CEP164-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP164→partner) and Y-score (partner→CEP164) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.143	+1.584	.026	.032	3	3
UCEC	ASNS →	+0.398	+1.362	<.001	.031	3	3
UCEC	ATM →	-0.383	-1.378	.004	.008	3	3
UCEC	JNK2 →	+0.201	+1.834	<.001	.013	3	2
BLCA	CD20 →	+0.165	+2.833	.001	.034	3	2
UCEC	JNK_pT183_Y185 →	-0.133	-1.362	.007	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

PCNA by CEP164 expression — UCEC

Explore this box plot interactively →