CEP162

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CEP162 mutation is significantly associated with the RNA expression of many other genes, with 4,201 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP162-associated genes across cancer lineages are MIR762HG, VDAC3, and TRUB2. Each is linked with CEP162 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP162-to-partner and partner-to-CEP162 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR762HG grouped by CEP162-low versus CEP162-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP162→partner) and Y-score (partner→CEP162) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR762HG →+0.365+2.112<.001<.00133
CESCVDAC3 →+0.470+3.351<.001.00433
UCECTRUB2 →+0.363+1.680<.001<.00133
CESCSLC25A33 →+0.582+3.189.002.00833
CESCRNF25 →+0.446+3.730.001<.00133
UCECC10orf67 →-0.251-2.024.005<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

MIR762HG by CEP162 expression — UCEC

Box plot of MIR762HG in CEP162-low vs CEP162-high samples in UCEC.

Explore this box plot interactively →

Exploration