CEP162

Across TCGA patient cohorts, CEP162 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP162-associated genes across cancer lineages are INPP4B, JNK2, and mTOR_pS2448. Each is linked with CEP162 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP162-to-partner and partner-to-CEP162 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by CEP162-low versus CEP162-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP162→partner) and Y-score (partner→CEP162) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.263	-1.999	.009	.008	3	2
UCEC	JNK2 →	+0.178	+1.584	.004	.005	3	2
UCEC	mTOR_pS2448 →	-0.112	-1.565	.017	.017	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.407	-2.169	.004	.003	3	2
UCEC	PDCD4 →	-0.487	-1.906	<.001	.014	3	2
UCEC	Src_pY527 →	-0.292	-1.574	.031	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

INPP4B by CEP162 expression — UCEC

Explore this box plot interactively →