CEP152

Across TCGA pan-cancer cohorts, CEP152 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CEP152’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CEP152 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEP152 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, BLCA, and KICH are the cancer types where CEP152 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP152 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.748	<.001	12	view →
BLCA	All	All	+1.069	<.001	10	view →
KICH	All	II,III,IV	+1.241	<.001	9	view →
THCA	Male	II,III,IV	−0.633	<.001	9	view →
LUSC	Male	II,III,IV	+1.103	<.001	8	view →
STAD	All	II,III,IV	+0.769	<.001	8	view →
LIHC	Female	All	+0.517	<.001	8	view →
KIRC	Male	All	+0.345	<.001	8	view →
COAD	All	II,III,IV	+0.497	<.001	6	view →
CHOL	Male	All	+1.458	<.001	3	view →
LUAD	All	All	+0.283	.005	3	view →
ESCA	All	All	+0.886	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CEP152–HNSC

Open the HNSC breakdown →