CEP131

Across TCGA pan-cancer cohorts, CEP131 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CEP131’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CEP131 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEP131 is over-expressed in tumor.

BLCA, KIRP, and HNSC are the cancer types where CEP131 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP131 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	All	+1.290	<.001	12	view →
KIRP	All	IV	+1.537	<.001	11	view →
HNSC	Male	III,IV	+1.390	<.001	11	view →
KIRC	Male	III,IV	+0.464	<.001	11	view →
LIHC	Female	II,III,IV	+2.077	<.001	9	view →
STAD	Male	II,III,IV	+1.588	<.001	9	view →
COAD	Female	II,III,IV	+0.955	<.001	9	view →
LUAD	All	All	+0.502	<.001	8	view →
LUSC	Male	II,III,IV	+0.975	<.001	6	view →
UCEC	All	All	+0.848	<.001	6	view →
CHOL	Male	All	+2.803	<.001	5	view →
ESCA	All	All	+0.835	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CEP131–BLCA

Open the BLCA breakdown →