CEP128

Across TCGA pan-cancer cohorts, CEP128 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CEP128 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CEP128 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CEP128 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where CEP128 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.595	1.000	.005	26	view →
PDAC	DFS	Median	III,IV	0.551	0.973	.016	10	view →
LUAD	OS	Median	III,IV	0.216	0.614	.017	3	view →
GBM	DFS	Quartile	All	0.572	0.271	.047	2	view →
LSCC	OS	Tertile	All	0.878	0.709	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CEP128–UCEC (OS)

Open the UCEC breakdown →