CEP120

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CEP120 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CEP120 data layer compared with 24 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher CEP120 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CEP120 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUSC show a favorable association.

PRAD, UCEC, and LUSC are the cancer types where CEP120 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PRADOSMedianAll0.4910.893<.0018view →
UCECDFSMedianAll0.9550.827.0208view →
LUSCDFSMedianAll1.0000.370.0394view →
LIHCOSMedianAll0.1920.514.0413view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CEP120–PRAD (OS)

Kaplan–Meier survival curve for CEP120 mutant vs wild-type samples in PRAD.

Open the PRAD breakdown →

Exploration