CEP120

Across TCGA cell cohorts, CEP120 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEP120-associated genes across cancer lineages are C18orf63, REG3A, and MAGEB5. Each is linked with CEP120 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP120-to-partner and partner-to-CEP120 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by CEP120-low versus CEP120-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP120→partner) and Y-score (partner→CEP120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	C18orf63 →	+0.006	+3.169	<.001	.005	3	2
BLOOD_Leukemia	REG3A →	+0.039	+2.979	<.001	.007	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_SCLC	ACER1 →	+0.048	+2.874	<.001	.007	3	1
LUNG_SCLC	PRAMEF33 →	+0.279	+3.614	<.001	.001	3	1
LARGE_INTESTINE	RBMY1B →	+0.004	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

C18orf63 by CEP120 expression — LUNG_SCLC

Explore this box plot interactively →