CEP112

Across TCGA patient cohorts, CEP112 mutation is significantly associated with the RNA expression of many other genes, with 4,536 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP112-associated genes across cancer lineages are SNX8, MTMR4, and CCDC47. Each is linked with CEP112 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP112-to-partner and partner-to-CEP112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX8 grouped by CEP112-low versus CEP112-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP112→partner) and Y-score (partner→CEP112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX8 →	+0.477	+1.747	<.001	<.001	3	3
UCEC	MTMR4 →	+0.387	+1.999	<.001	.002	3	3
UCEC	CCDC47 →	+0.392	+2.042	.006	.004	3	3
UCEC	POLR1E →	+0.317	+1.369	.003	.004	3	3
UCEC	CBX8 →	+0.320	+2.139	.003	<.001	3	3
UCEC	URB1-AS1 →	+0.326	+2.127	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

SNX8 by CEP112 expression — UCEC

Explore this box plot interactively →